INHIBITION OF METHYLTRANSFERASE ACTIVITY OF ENHANCER OF ZESTE 2 LEADS TO ENHANCED LIPID ACCUMULATION AND ALTERED CHROMATIN STATUS IN ZEBRAFISH

Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish

Abstract Background Recent studies indicate that exposure to environmental chemicals may increase susceptibility to developing metabolic diseases.This susceptibility may in part be caused by changes to the epigenetic landscape which consequently affect gene expression and lead to changes in lipid metabolism.The epigenetic modifier enhancer of zeste

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A quantitative comparison between the mHand Adapt passive adjustable hand prosthesis and its predecessor, the Delft Self-Grasping Hand.

IntroductionThe Delft Self-Grasping Hand (SGH) is an adjustable passive hand prosthesis that relies on wrist flexion to adjust the aperture of its grasp.The mechanism requires engagement of the contralateral hand meaning that hand is not available for other tasks.A commercialised Play Mat version of this prosthesis, known as the mHand Adapt, includ

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